The Methotrexate / Misoprostol medical abortion starts with injections of Methotrexate. This medication causes the early developing pregnancy to stop growing. The injections are very safe and are as effective as RU-486. On the third day after the injections you will take Misoprostol tablets by mouth. These tablets will promote cramping and miscarriage of the pregnancy. Vaginal bleeding may start 1 to 3 weeks from the initial injection. Expect your bleeding to last between 9 – 16 days and as long as 30 days.

Three steps to a Methotrexate / Misoprostol medical abortion:

  1. You will receive your dose of Methotrexate in the office. Methotrexate stops the growth of the pregnancy in the uterus. It can also stop the growth of pregnancies that develop in a fallopian tube— ectopic pregnancies.
  2. You will take a second medication — Misoprostol. Misoprostol softens the cervix and causes the uterus to contract and empty.  You will take the Misoprostol three days after taking Methotrexate. After you take the Misoprostol you will most likely start to bleed heavily within hours or days. This is the abortion. You may see large blood clots or tissue during the initial bleeding.
  3. You will return to our office for a follow-up visit in two to three weeks.  We need to be certain the abortion is complete and that you are well. We will do a sonogram and a pregnancy test at your follow up visit.  The RH factor of your blood type will be determined at your initial visit, and, if you have RH negative blood you will receive a Rhogam injection the day you begin your procedure. You will receive written information that describes the entire process and you will have a private consultation with our physician to address any questions or concerns.